Development and characterization of protein kinase B/AKT isoform-specific nanobodies

The serine/threonine protein kinase AKT is frequently over-activated in cancer and is associated with poor prognosis. As a central node in the PI3K/AKT/mTOR pathway, which regulates various processes considered to be hallmarks of cancer, this kinase has become a prime target for cancer therapy. Howe...

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Detalles Bibliográficos
Autores principales: Merckaert, Tijs, Zwaenepoel, Olivier, Gevaert, Kris, Gettemans, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549812/
https://www.ncbi.nlm.nih.gov/pubmed/33045011
http://dx.doi.org/10.1371/journal.pone.0240554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549812/
https://www.ncbi.nlm.nih.gov/pubmed/33045011
http://dx.doi.org/10.1371/journal.pone.0240554

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