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The dimerisable Cre recombinase allows conditional genome editing in the mosquito stages of Plasmodium berghei

Asexual blood stages of the malaria parasite are readily amenable to genetic modification via homologous recombination, allowing functional studies of parasite genes that are not essential in this part of the life cycle. However, conventional reverse genetics cannot be applied for the functional ana...

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Detalles Bibliográficos
Autores principales: Fernandes, Priyanka, Briquet, Sylvie, Patarot, Delphine, Loubens, Manon, Hoareau-Coudert, Bénédicte, Silvie, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549836/
https://www.ncbi.nlm.nih.gov/pubmed/33044964
http://dx.doi.org/10.1371/journal.pone.0236616