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The dimerisable Cre recombinase allows conditional genome editing in the mosquito stages of Plasmodium berghei
Asexual blood stages of the malaria parasite are readily amenable to genetic modification via homologous recombination, allowing functional studies of parasite genes that are not essential in this part of the life cycle. However, conventional reverse genetics cannot be applied for the functional ana...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549836/ https://www.ncbi.nlm.nih.gov/pubmed/33044964 http://dx.doi.org/10.1371/journal.pone.0236616 |