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Tobacco Hornworm (Manduca sexta) caterpillars as a novel host model for the study of fungal virulence and drug efficacy

The two leading yeast pathogens of humans, Candida albicans and Cryptococcus neoformans, cause systemic infections in >1.4 million patients worldwide with mortality rates approaching 75%. It is thus imperative to study fungal virulence mechanisms, efficacy of antifungal drugs, and host response p...

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Detalles Bibliográficos
Autores principales: Lyons, Naomi, Softley, Isabel, Balfour, Andrew, Williamson, Carolyn, O’Brien, Heath E., Shetty, Amol C., Bruno, Vincent M., Diezmann, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549948/
https://www.ncbi.nlm.nih.gov/pubmed/32842847
http://dx.doi.org/10.1080/21505594.2020.1806665