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A novel biosafety level 2 compliant tuberculosis infection model using a ΔleuDΔpanCD double auxotroph of Mycobacterium tuberculosis H37Rv and Galleria mellonella

Mammalian infection models have contributed significantly to our understanding of the host-mycobacterial interaction, revealing potential mechanisms and targets for novel antimycobacterial therapeutics. However, the use of conventional mammalian models such as mice, are typically expensive, high mai...

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Detalles Bibliográficos
Autores principales: Asai, Masanori, Li, Yanwen, Spiropoulos, John, Cooley, William, Everest, David, Robertson, Brian D., Langford, Paul R., Newton, Sandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550006/
https://www.ncbi.nlm.nih.gov/pubmed/32530737
http://dx.doi.org/10.1080/21505594.2020.1781486