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Non-invasive detection of biliary tract cancer by low-coverage whole genome sequencing from plasma cell-free DNA: A prospective cohort study

BACKGROUND: The diagnosis of biliary tract cancer (BTC) is challenging in clinical practice. We performed a prospective study to evaluate the value of plasma copy number variation (CNV) assays in diagnosing BTC. METHODS: 47 treatment-naïve patients with suspicious biliary lesions were recruited. Pla...

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Detalles Bibliográficos
Autores principales: Wang, Xiang, Fu, Xiao-Hui, Qian, Zi-Liang, Zhao, Teng, Duan, An-Qi, Ruan, Xiang, Zhu, Bin, Yin, Lei, Zhang, Yong-Jie, Yu, Wen-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550068/
https://www.ncbi.nlm.nih.gov/pubmed/33059123
http://dx.doi.org/10.1016/j.tranon.2020.100908