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Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Understanding the genetic regulation of organ structure is a fundamental problem in developmental biology. Here, we use egg-producing structures of insect ovaries, called ovarioles, to deduce systems-level gene regulatory relationships from quantitative functional genetic analysis. We previously sho...

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Detalles Bibliográficos
Autores principales: Kumar, Tarun, Blondel, Leo, Extavour, Cassandra G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550192/
https://www.ncbi.nlm.nih.gov/pubmed/32901612
http://dx.doi.org/10.7554/eLife.54082