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A simple method for modeling amyloid kinetics featuring position biased fiber breakage

A mathematical model of amyloid fiber formation is described that is able to simply specify different rates of fiber breakage at internal versus end regions. This Note presents the derivation of the relevant equations and provides results showing the dramatic effects of position biased fiber breakag...

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Detalles Bibliográficos
Autor principal: Hall, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550252/
https://www.ncbi.nlm.nih.gov/pubmed/33110736
http://dx.doi.org/10.2142/biophysico.BSJ-2020003