A simple method for modeling amyloid kinetics featuring position biased fiber breakage

A mathematical model of amyloid fiber formation is described that is able to simply specify different rates of fiber breakage at internal versus end regions. This Note presents the derivation of the relevant equations and provides results showing the dramatic effects of position biased fiber breakag...

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Detalles Bibliográficos
Autor principal: Hall, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan 2020
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550252/
https://www.ncbi.nlm.nih.gov/pubmed/33110736
http://dx.doi.org/10.2142/biophysico.BSJ-2020003
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author Hall, Damien
author_facet Hall, Damien
author_sort Hall, Damien
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description A mathematical model of amyloid fiber formation is described that is able to simply specify different rates of fiber breakage at internal versus end regions. This Note presents the derivation of the relevant equations and provides results showing the dramatic effects of position biased fiber breakage on the kinetics of amyloid growth.
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spelling pubmed-75502522020-10-26 A simple method for modeling amyloid kinetics featuring position biased fiber breakage Hall, Damien Biophys Physicobiol Note A mathematical model of amyloid fiber formation is described that is able to simply specify different rates of fiber breakage at internal versus end regions. This Note presents the derivation of the relevant equations and provides results showing the dramatic effects of position biased fiber breakage on the kinetics of amyloid growth. The Biophysical Society of Japan 2020-03-20 /pmc/articles/PMC7550252/ /pubmed/33110736 http://dx.doi.org/10.2142/biophysico.BSJ-2020003 Text en 2020 THE BIOPHYSICAL SOCIETY OF JAPAN https://creativecommons.org/licenses/by-nc-sa/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Inter­national License. To view a copy of this license, visit 
https://creativecommons.org/licenses/by-nc-sa/4.0/.
spellingShingle Note
Hall, Damien
A simple method for modeling amyloid kinetics featuring position biased fiber breakage
title A simple method for modeling amyloid kinetics featuring position biased fiber breakage
title_full A simple method for modeling amyloid kinetics featuring position biased fiber breakage
title_fullStr A simple method for modeling amyloid kinetics featuring position biased fiber breakage
title_full_unstemmed A simple method for modeling amyloid kinetics featuring position biased fiber breakage
title_short A simple method for modeling amyloid kinetics featuring position biased fiber breakage
title_sort simple method for modeling amyloid kinetics featuring position biased fiber breakage
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550252/
https://www.ncbi.nlm.nih.gov/pubmed/33110736
http://dx.doi.org/10.2142/biophysico.BSJ-2020003
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