AKT-induced lncRNA VAL promotes EMT-independent metastasis through diminishing Trim16-dependent Vimentin degradation

Despite the importance of AKT overactivation in tumor progression, results from clinical trials of various AKT inhibitors remain suboptimal, suggesting that AKT-driven tumor metastasis needs to be further understood. Herein, based on long non-coding RNA (lncRNA) profiling induced by active AKT, we i...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Han, Lian, Rong, Li, Yun, Liu, Chenying, Liang, Shujun, Li, Wei, Tao, Tianyu, Wu, Xingui, Ye, Yaokai, Yang, Xia, Han, Jian, Chen, Xuwei, Li, Jun, He, Yukai, Li, Mengfeng, Wu, Jueheng, Cai, Junchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550350/
https://www.ncbi.nlm.nih.gov/pubmed/33046716
http://dx.doi.org/10.1038/s41467-020-18929-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550350/
https://www.ncbi.nlm.nih.gov/pubmed/33046716
http://dx.doi.org/10.1038/s41467-020-18929-0

Ejemplares similares