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Neural Progenitor Cells Undergoing Yap/Tead-Mediated Enhanced Self-Renewal Form Heterotopias More Easily in the Diencephalon than in the Telencephalon

Spatiotemporally ordered production of cells is essential for brain development. Normally, most undifferentiated neural progenitor cells (NPCs) face the apical (ventricular) surface of embryonic brain walls. Pathological detachment of NPCs from the apical surface and their invasion of outer neuronal...

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Detalles Bibliográficos
Autores principales: Saito, Kanako, Kawasoe, Ryotaro, Sasaki, Hiroshi, Kawaguchi, Ayano, Miyata, Takaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550386/
https://www.ncbi.nlm.nih.gov/pubmed/28879493
http://dx.doi.org/10.1007/s11064-017-2390-x