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Influence of metformin on HIF-1 pathway in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is defined as plasma cells malignancy, developing in the bone marrow. At the beginning of the disease, the malignant plasma cells are dependent on bone marrow microenvironment, providing growth and survival factors. Importantly, the recent studies pointed hypoxia as...

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Detalles Bibliográficos
Autores principales: Kocemba-Pilarczyk, Kinga A., Trojan, Sonia, Ostrowska, Barbara, Lasota, Małgorzata, Dudzik, Paulina, Kusior, Dorota, Kot, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550387/
https://www.ncbi.nlm.nih.gov/pubmed/32715434
http://dx.doi.org/10.1007/s43440-020-00142-x