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When STING Meets Viruses: Sensing, Trafficking and Response

To effectively defend against microbial pathogens, the host cells mount antiviral innate immune responses by producing interferons (IFNs), and hundreds of IFN-stimulated genes (ISGs). Upon recognition of cytoplasmic viral or bacterial DNAs and abnormal endogenous DNAs, the DNA sensor cGAS synthesize...

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Detalles Bibliográficos
Autores principales: Li, Zhaohe, Cai, Siqi, Sun, Yutong, Li, Li, Ding, Siyuan, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550420/
https://www.ncbi.nlm.nih.gov/pubmed/33133062
http://dx.doi.org/10.3389/fimmu.2020.02064