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Is There an Interplay Between the Functional Domains of IRAP?

As a member of the M1 family of aminopeptidases, insulin regulated aminopeptidase (IRAP) is characterized by distinct binding motifs at the active site in the C-terminal domain that mediate the catalysis of peptide substrates. However, what makes IRAP unique in this family of enzymes is that it also...

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Detalles Bibliográficos
Autores principales: Vear, Anika, Gaspari, Tracey, Thompson, Philip, Chai, Siew Yeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550531/
https://www.ncbi.nlm.nih.gov/pubmed/33134302
http://dx.doi.org/10.3389/fcell.2020.585237