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The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections

G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of fatty acids, insulin secretion, and inflammation. However, the function of this receptor in human neutrophils, one of the first leukocytes to arrive at the site of infection, remains to be fully elucidated. In the pre...

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Detalles Bibliográficos
Autores principales: Souza, Patricia R., Walker, Mary E., Goulding, Nicolas J., Dalli, Jesmond, Perretti, Mauro, Norling, Lucy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550532/
https://www.ncbi.nlm.nih.gov/pubmed/33133087
http://dx.doi.org/10.3389/fimmu.2020.573019