Cargando…
The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections
G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of fatty acids, insulin secretion, and inflammation. However, the function of this receptor in human neutrophils, one of the first leukocytes to arrive at the site of infection, remains to be fully elucidated. In the pre...
Autores principales: | Souza, Patricia R., Walker, Mary E., Goulding, Nicolas J., Dalli, Jesmond, Perretti, Mauro, Norling, Lucy V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550532/ https://www.ncbi.nlm.nih.gov/pubmed/33133087 http://dx.doi.org/10.3389/fimmu.2020.573019 |
Ejemplares similares
-
GPR120 Agonist GW9508 Ameliorated Cellular Senescence
Induced by ox-LDL
por: Liu, Ruijie, et al.
Publicado: (2020) -
Heterogeneity in Neutrophil Microparticles Reveals Distinct Proteome and Functional Properties
por: Dalli, Jesmond, et al.
Publicado: (2013) -
Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow
por: Dalli, Jesmond, et al.
Publicado: (2012) -
G-protein-coupled receptor 40 agonist GW9508 potentiates glucose-stimulated insulin secretion through activation of protein kinase Cα and ε in INS-1 cells
por: Hashimoto, Takuya, et al.
Publicado: (2019) -
3D-Printed Bioactive Scaffold Loaded with GW9508 Promotes Critical-Size Bone Defect Repair by Regulating Intracellular Metabolism
por: Huang, Fangli, et al.
Publicado: (2023)