Downregulation of p53 by Insufficient CTCF in CD4(+) T Cells Is an Important Factor Inducing Acute Graft-Versus-Host Disease

Recent evidence indicates that p53 plays a protective role against various systemic autoimmune diseases by suppressing pro-inflammatory cytokine production and reducing the number of pathogenic T cells. However, whether abnormal p53 expression participates in the development of acute graft-versus-ho...

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Detalles Bibliográficos
Autores principales: Hua, Juan, Chen, Yan, Fu, Bin, Chen, Xu, Xu, Xue-jun, Yang, Shuang-Hui, Chen, Cong, Xu, Ya-jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550539/
https://www.ncbi.nlm.nih.gov/pubmed/33133081
http://dx.doi.org/10.3389/fimmu.2020.568637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550539/
https://www.ncbi.nlm.nih.gov/pubmed/33133081
http://dx.doi.org/10.3389/fimmu.2020.568637

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