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Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of Outcome

OBJECTIVES: In March 2020, the World Health Organization declared that an infectious respiratory disease caused by a new severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2, causing coronavirus disease 2019 (COVID-19)] became a pandemic. In our study, we have analyzed a large publicly availa...

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Detalles Bibliográficos
Autores principales: Shikov, Anton E., Barbitoff, Yury A., Glotov, Andrey S., Danilova, Maria M., Tonyan, Ziravard N., Nasykhova, Yulia A., Mikhailova, Anastasia A., Bespalova, Olesya N., Kalinin, Roman S., Mirzorustamova, Azizahon M., Kogan, Igor Yu, Baranov, Vladislav S., Chernov, Alexander N., Pavlovich, Dragana M., Azarenko, Sergey V., Fedyakov, Mikhail A., Tsay, Victoria V., Eismont, Yuri A., Romanova, Olga V., Hobotnikov, Dmitry N., Vologzhanin, Dmitry A., Mosenko, Sergei V., Ponomareva, Tatiana A., Talts, Yana A., Anisenkova, Anna U., Lisovets, Dmitrii G., Sarana, Andrey M., Urazov, Stanislav P., Scherbak, Sergey G., Glotov, Oleg S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550667/
https://www.ncbi.nlm.nih.gov/pubmed/33133145
http://dx.doi.org/10.3389/fgene.2020.551220