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WAVE1 and WAVE2 have distinct and overlapping roles in controlling actin assembly at the leading edge

SCAR/WAVE proteins and Arp2/3 complex assemble branched actin networks at the leading edge. Two isoforms of SCAR/WAVE, WAVE1 and WAVE2, reside at the leading edge, yet it has remained unclear whether they perform similar or distinct roles. Further, there have been conflicting reports about the Arp2/...

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Detalles Bibliográficos
Autores principales: Tang, Qing, Schaks, Matthias, Koundinya, Neha, Yang, Changsong, Pollard, Luther W., Svitkina, Tatyana M., Rottner, Klemens, Goode, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550694/
https://www.ncbi.nlm.nih.gov/pubmed/32697617
http://dx.doi.org/10.1091/mbc.E19-12-0705