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Regulation of NRF1, a master transcription factor of proteasome genes: implications for cancer and neurodegeneration
The ability to sense proteasome insufficiency and respond by directing the transcriptional synthesis of de novo proteasomes is a trait that is conserved in evolution and is found in organisms ranging from yeast to humans. This homeostatic mechanism in mammalian cells is driven by the transcription f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550695/ https://www.ncbi.nlm.nih.gov/pubmed/32924844 http://dx.doi.org/10.1091/mbc.E20-04-0238 |