The conserved AAA-ATPase PCH-2 (TRIP13) regulates spindle checkpoint strength

Spindle checkpoint strength is dictated by the number of unattached kinetochores, cell volume, and cell fate. We show that the conserved AAA-ATPase PCH-2/TRIP13, which remodels the checkpoint effector Mad2 from an active conformation to an inactive one, controls checkpoint strength in Caenorhabditis...

Descripción completa

Detalles Bibliográficos
Autores principales: Défachelles, Lénaïg, Russo, Anna E., Nelson, Christian R., Bhalla, Needhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550697/
https://www.ncbi.nlm.nih.gov/pubmed/32697629
http://dx.doi.org/10.1091/mbc.E20-05-0310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550697/
https://www.ncbi.nlm.nih.gov/pubmed/32697629
http://dx.doi.org/10.1091/mbc.E20-05-0310

Ejemplares similares