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The Borealin dimerization domain interacts with Sgo1 to drive Aurora B–mediated spindle assembly
The chromosomal passenger complex (CPC), which includes the kinase Aurora B, is a master regulator of meiotic and mitotic processes that ensure the equal segregation of chromosomes. Sgo1 is thought to play a major role in the recruitment of the CPC to chromosomes, but the molecular mechanism and con...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550704/ https://www.ncbi.nlm.nih.gov/pubmed/32697622 http://dx.doi.org/10.1091/mbc.E20-05-0341 |