Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine

INTRODUCTION: Gln‐1062 (MEMOGAIN) is an intranasally administered lipophilic prodrug of galantamine. Based on high brain‐to‐blood concentrations observed in pre‐clinical studies, Gln‐1062 is expected to have superior cognitive efficacy compared to oral galantamine. METHODS: Forty‐eight healthy elder...

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Detalles Bibliográficos
Autores principales: Bakker, Charlotte, van der Aart, Jasper, Hart, Ellen P., Klaassen, Erica S., Bergmann, Kirsten R., van Esdonk, Michiel J., Kay, Denis G., Groeneveld, Geert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551138/
https://www.ncbi.nlm.nih.gov/pubmed/33083515
http://dx.doi.org/10.1002/trc2.12093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551138/
https://www.ncbi.nlm.nih.gov/pubmed/33083515
http://dx.doi.org/10.1002/trc2.12093

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