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Betulinic Acid Attenuates Oxidative Stress in the Thymus Induced by Acute Exposure to T-2 Toxin via Regulation of the MAPK/Nrf2 Signaling Pathway

T-2 toxin, the most toxic of the trichothecenes, is widely found in grains and feeds, and its intake poses serious risks to the health of humans and animals. An important cytotoxicity mechanism of T-2 toxin is the production of excess free radicals, which in turn leads to oxidative stress. Betulinic...

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Detalles Bibliográficos
Autores principales: Zhu, Lijuan, Yi, Xianglian, Ma, Chaoyang, Luo, Chenxi, Kong, Li, Lin, Xing, Gao, Xinyu, Yuan, Zhihang, Wen, Lixin, Li, Rongfang, Wu, Jing, Yi, Jine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551141/
https://www.ncbi.nlm.nih.gov/pubmed/32842569
http://dx.doi.org/10.3390/toxins12090540