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Old Drugs with New Tricks: Efficacy of Fluoroquinolones to Suppress Replication of Flaviviruses

Repurposing FDA-approved compounds could provide the fastest route to alleviate the burden of disease caused by flaviviruses. In this study, three fluoroquinolones, enoxacin, difloxacin and ciprofloxacin, curtailed replication of flaviviruses Zika (ZIKV), dengue (DENV), Langat (LGTV) and Modoc (MODV...

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Detalles Bibliográficos
Autores principales: Scroggs, Stacey L. P., Andrade, Christy C., Chinnasamy, Ramesh, Azar, Sasha R., Schirtzinger, Erin E., Garcia, Erin I., Arterburn, Jeffrey B., Hanley, Kathryn A., Rossi, Shannan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551155/
https://www.ncbi.nlm.nih.gov/pubmed/32933138
http://dx.doi.org/10.3390/v12091022