IIAEK Targets Intestinal Alkaline Phosphatase (IAP) to Improve Cholesterol Metabolism with a Specific Activation of IAP and Downregulation of ABCA1

IIAEK (Ile-Ile-Ala-Glu-Lys, lactostatin) is a novel cholesterol-lowering pentapeptide derived from bovine milk β-lactoglobulin. However, the molecular mechanisms underlying the IIAEK-mediated suppression of intestinal cholesterol absorption are unknown. Therefore, we evaluated the effects of IIAEK o...

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Detalles Bibliográficos
Autores principales: Takeuchi, Asahi, Hisamatsu, Kentaro, Okumura, Natsuki, Sugimitsu, Yuki, Yanase, Emiko, Ueno, Yoshihito, Nagaoka, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551322/
https://www.ncbi.nlm.nih.gov/pubmed/32961978
http://dx.doi.org/10.3390/nu12092859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551322/
https://www.ncbi.nlm.nih.gov/pubmed/32961978
http://dx.doi.org/10.3390/nu12092859

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