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IIAEK Targets Intestinal Alkaline Phosphatase (IAP) to Improve Cholesterol Metabolism with a Specific Activation of IAP and Downregulation of ABCA1
IIAEK (Ile-Ile-Ala-Glu-Lys, lactostatin) is a novel cholesterol-lowering pentapeptide derived from bovine milk β-lactoglobulin. However, the molecular mechanisms underlying the IIAEK-mediated suppression of intestinal cholesterol absorption are unknown. Therefore, we evaluated the effects of IIAEK o...
Autores principales: | Takeuchi, Asahi, Hisamatsu, Kentaro, Okumura, Natsuki, Sugimitsu, Yuki, Yanase, Emiko, Ueno, Yoshihito, Nagaoka, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551322/ https://www.ncbi.nlm.nih.gov/pubmed/32961978 http://dx.doi.org/10.3390/nu12092859 |
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