Cargando…

Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling

OBJECTIVE: Although the hypothalamus is crucial for peripheral metabolism control, the signals in specific neurons involved remain poorly understood. The aim of our current study was to explore the role of the hypothalamic gene mothers against decapentaplegic homolog 7 (Smad7) in peripheral glucose...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Feixiang, Yin, Hanrui, Deng, Yalan, Jiao, Fuxin, Jiang, Haizhou, Niu, Yuguo, Chen, Shanghai, Ying, Hao, Zhai, Qiwei, Chen, Yan, Guo, Feifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551358/
https://www.ncbi.nlm.nih.gov/pubmed/32971298
http://dx.doi.org/10.1016/j.molmet.2020.101084