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Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling
OBJECTIVE: Although the hypothalamus is crucial for peripheral metabolism control, the signals in specific neurons involved remain poorly understood. The aim of our current study was to explore the role of the hypothalamic gene mothers against decapentaplegic homolog 7 (Smad7) in peripheral glucose...
Autores principales: | Yuan, Feixiang, Yin, Hanrui, Deng, Yalan, Jiao, Fuxin, Jiang, Haizhou, Niu, Yuguo, Chen, Shanghai, Ying, Hao, Zhai, Qiwei, Chen, Yan, Guo, Feifan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551358/ https://www.ncbi.nlm.nih.gov/pubmed/32971298 http://dx.doi.org/10.1016/j.molmet.2020.101084 |
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