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Rodent model of disuse-induced bone loss by hind limb injection with botulinum toxin A

Bone loss materializes rapidly after immobilization or mechanical unloading. Hind limb injection with botulinum toxin A (BTX) is a highly reproducible animal model for disuse-induced bone loss. Here we describe an easy-to-use and enhanced version of the method employing multiple hind limb injections...

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Detalles Bibliográficos
Autores principales: Brent, Mikkel Bo, Lodberg, Andreas, Thomsen, Jesper Skovhus, Brüel, Annemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551361/
https://www.ncbi.nlm.nih.gov/pubmed/33083241
http://dx.doi.org/10.1016/j.mex.2020.101079