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Trim24 and Trim33 Play a Role in Epigenetic Silencing of Retroviruses in Embryonic Stem Cells

Embryonic stem cells (ESC) have the ability to epigenetically silence endogenous and exogenous retroviral sequences. Trim28 plays an important role in establishing this silencing, but less is known about the role other Trim proteins play. The Tif1 family is a sub-group of the Trim family, which poss...

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Detalles Bibliográficos
Autores principales: Margalit, Liad, Strauss, Carmit, Tal, Ayellet, Schlesinger, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551373/
https://www.ncbi.nlm.nih.gov/pubmed/32932986
http://dx.doi.org/10.3390/v12091015