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CD47 as a Potential Target to Therapy for Infectious Diseases

The integrin associated protein (CD47) is a widely and moderately expressed glycoprotein in all healthy cells. Cancer cells are known to induce increased CD47 expression. Similar to cancer cells, all immune cells can upregulate their CD47 surface expression during infection. The CD47-SIRPa interacti...

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Detalles Bibliográficos
Autores principales: Cham, Lamin B., Adomati, Tom, Li, Fanghui, Ali, Murtaza, Lang, Karl S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551396/
https://www.ncbi.nlm.nih.gov/pubmed/32882841
http://dx.doi.org/10.3390/antib9030044