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CD1d Selectively Down Regulates the Expression of the Oxidized Phospholipid-Specific E06 IgM Natural Antibody in Ldlr(−/−) Mice

Natural antibodies (NAbs) are important regulators of tissue homeostasis and inflammation and are thought to have diverse protective roles in a variety of pathological states. E06 is a T15 idiotype IgM NAb exclusively produced by B-1 cells, which recognizes the phosphocholine (PC) head group in oxid...

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Detalles Bibliográficos
Autores principales: Biswas, Tapan K., VanderLaan, Paul A., Que, Xuchu, Gonen, Ayelet, Krishack, Paulette, Binder, Christoph J., Witztum, Joseph L., Getz, Godfrey S., Reardon, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551411/
https://www.ncbi.nlm.nih.gov/pubmed/32635160
http://dx.doi.org/10.3390/antib9030030