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CD1d Selectively Down Regulates the Expression of the Oxidized Phospholipid-Specific E06 IgM Natural Antibody in Ldlr(−/−) Mice
Natural antibodies (NAbs) are important regulators of tissue homeostasis and inflammation and are thought to have diverse protective roles in a variety of pathological states. E06 is a T15 idiotype IgM NAb exclusively produced by B-1 cells, which recognizes the phosphocholine (PC) head group in oxid...
Autores principales: | Biswas, Tapan K., VanderLaan, Paul A., Que, Xuchu, Gonen, Ayelet, Krishack, Paulette, Binder, Christoph J., Witztum, Joseph L., Getz, Godfrey S., Reardon, Catherine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551411/ https://www.ncbi.nlm.nih.gov/pubmed/32635160 http://dx.doi.org/10.3390/antib9030030 |
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