Dietary Oxalate Intake and Kidney Outcomes

Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known physiological function in humans. It is predominantly eliminated by the kidneys through glomerular filtration and tubular secretion. Regardless of the cause, the increased load of dietary oxalate presented to the...

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Autores principales: Bargagli, Matteo, Tio, Maria Clarissa, Waikar, Sushrut S., Ferraro, Pietro Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551439/
https://www.ncbi.nlm.nih.gov/pubmed/32887293
http://dx.doi.org/10.3390/nu12092673
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author Bargagli, Matteo
Tio, Maria Clarissa
Waikar, Sushrut S.
Ferraro, Pietro Manuel
author_facet Bargagli, Matteo
Tio, Maria Clarissa
Waikar, Sushrut S.
Ferraro, Pietro Manuel
author_sort Bargagli, Matteo
collection PubMed
description Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known physiological function in humans. It is predominantly eliminated by the kidneys through glomerular filtration and tubular secretion. Regardless of the cause, the increased load of dietary oxalate presented to the kidneys has been linked to different kidney-related conditions and injuries, including calcium oxalate nephrolithiasis, acute and chronic kidney disease. In this paper, we review the current literature on the association between dietary oxalate intake and kidney outcomes.
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spelling pubmed-75514392020-10-14 Dietary Oxalate Intake and Kidney Outcomes Bargagli, Matteo Tio, Maria Clarissa Waikar, Sushrut S. Ferraro, Pietro Manuel Nutrients Review Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known physiological function in humans. It is predominantly eliminated by the kidneys through glomerular filtration and tubular secretion. Regardless of the cause, the increased load of dietary oxalate presented to the kidneys has been linked to different kidney-related conditions and injuries, including calcium oxalate nephrolithiasis, acute and chronic kidney disease. In this paper, we review the current literature on the association between dietary oxalate intake and kidney outcomes. MDPI 2020-09-02 /pmc/articles/PMC7551439/ /pubmed/32887293 http://dx.doi.org/10.3390/nu12092673 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bargagli, Matteo
Tio, Maria Clarissa
Waikar, Sushrut S.
Ferraro, Pietro Manuel
Dietary Oxalate Intake and Kidney Outcomes
title Dietary Oxalate Intake and Kidney Outcomes
title_full Dietary Oxalate Intake and Kidney Outcomes
title_fullStr Dietary Oxalate Intake and Kidney Outcomes
title_full_unstemmed Dietary Oxalate Intake and Kidney Outcomes
title_short Dietary Oxalate Intake and Kidney Outcomes
title_sort dietary oxalate intake and kidney outcomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551439/
https://www.ncbi.nlm.nih.gov/pubmed/32887293
http://dx.doi.org/10.3390/nu12092673
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