Viriditoxin Stabilizes Microtubule Polymers in SK-OV-3 Cells and Exhibits Antimitotic and Antimetastatic Potential

Microtubules play a crucial role in mitosis and are attractive targets for cancer therapy. Recently, we isolated viriditoxin, a cytotoxic and antibacterial compound, from a marine fungus Paecilomyces variotii. Viriditoxin has been reported to inhibit the polymerization of bacterial FtsZ, a tubulin-l...

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Detalles Bibliográficos
Autores principales: Su, Mingzhi, Zhao, Changhao, Li, Dandan, Cao, Jiafu, Ju, Zhiran, Kim, Eun La, Jung, Young-Suk, Jung, Jee H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551567/
https://www.ncbi.nlm.nih.gov/pubmed/32867174
http://dx.doi.org/10.3390/md18090445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551567/
https://www.ncbi.nlm.nih.gov/pubmed/32867174
http://dx.doi.org/10.3390/md18090445

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