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Viriditoxin Stabilizes Microtubule Polymers in SK-OV-3 Cells and Exhibits Antimitotic and Antimetastatic Potential

Microtubules play a crucial role in mitosis and are attractive targets for cancer therapy. Recently, we isolated viriditoxin, a cytotoxic and antibacterial compound, from a marine fungus Paecilomyces variotii. Viriditoxin has been reported to inhibit the polymerization of bacterial FtsZ, a tubulin-l...

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Detalles Bibliográficos
Autores principales:	Su, Mingzhi, Zhao, Changhao, Li, Dandan, Cao, Jiafu, Ju, Zhiran, Kim, Eun La, Jung, Young-Suk, Jung, Jee H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551567/ https://www.ncbi.nlm.nih.gov/pubmed/32867174 http://dx.doi.org/10.3390/md18090445

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