Venezuelan Equine Encephalitis Virus nsP3 Phosphorylation Can Be Mediated by IKKβ Kinase Activity and Abrogation of Phosphorylation Inhibits Negative-Strand Synthesis

Venezuelan equine encephalitis virus (VEEV), a mosquito transmitted alphavirus of the Togaviridae family, can cause a highly inflammatory and encephalitic disease upon infection. Although a category B select agent, no FDA-approved vaccines or therapeutics against VEEV currently exist. We previously...

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Detalles Bibliográficos
Autores principales: Bakovic, Allison, Bhalla, Nishank, Kortchak, Stephanie, Sun, Chengqun, Zhou, Weidong, Ahmed, Aslaa, Risner, Kenneth, Klimstra, William B., Narayanan, Aarthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551587/
https://www.ncbi.nlm.nih.gov/pubmed/32933112
http://dx.doi.org/10.3390/v12091021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551587/
https://www.ncbi.nlm.nih.gov/pubmed/32933112
http://dx.doi.org/10.3390/v12091021

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