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Venezuelan Equine Encephalitis Virus nsP3 Phosphorylation Can Be Mediated by IKKβ Kinase Activity and Abrogation of Phosphorylation Inhibits Negative-Strand Synthesis
Venezuelan equine encephalitis virus (VEEV), a mosquito transmitted alphavirus of the Togaviridae family, can cause a highly inflammatory and encephalitic disease upon infection. Although a category B select agent, no FDA-approved vaccines or therapeutics against VEEV currently exist. We previously...
Autores principales: | Bakovic, Allison, Bhalla, Nishank, Kortchak, Stephanie, Sun, Chengqun, Zhou, Weidong, Ahmed, Aslaa, Risner, Kenneth, Klimstra, William B., Narayanan, Aarthi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551587/ https://www.ncbi.nlm.nih.gov/pubmed/32933112 http://dx.doi.org/10.3390/v12091021 |
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