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Capturing Membrane Protein Ribosome Nascent Chain Complexes in a Native-like Environment for Co-translational Studies

[Image: see text] Co-translational folding studies of membrane proteins lag behind cytosolic protein investigations largely due to the technical difficulty in maintaining membrane lipid environments for correct protein folding. Stalled ribosome-bound nascent chain complexes (RNCs) can give snapshots...

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Detalles Bibliográficos
Autores principales: Pellowe, Grant A., Findlay, Heather E., Lee, Karen, Gemeinhardt, Tim M., Blackholly, Laura R., Reading, Eamonn, Booth, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551657/
https://www.ncbi.nlm.nih.gov/pubmed/32627541
http://dx.doi.org/10.1021/acs.biochem.0c00423