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How Do mAbs Make Use of Complement to Kill Cancer Cells? The Role of Ca(2+)

We examined the kinetics and mechanisms by which monoclonal antibodies (mAbs) utilize complement to rapidly kill targeted cancer cells. Based on results from flow cytometry, confocal microscopy and high-resolution digital imaging experiments, the general patterns which have emerged reveal cytotoxic...

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Detalles Bibliográficos
Autores principales: Taylor, Ronald P., Lindorfer, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551823/
https://www.ncbi.nlm.nih.gov/pubmed/32899722
http://dx.doi.org/10.3390/antib9030045