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NPC1L1 Facilitates Sphingomyelin Absorption and Regulates Diet-Induced Production of VLDL/LDL-associated S1P

Niemann-Pick C1-Like 1 (NPC1L1) is a cholesterol importer and target of ezetimibe, a cholesterol absorption inhibitor used clinically for dyslipidemia. Recent studies demonstrated that NPC1L1 regulates the intestinal absorption of several fat-soluble nutrients, in addition to cholesterol. The study...

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Detalles Bibliográficos
Autores principales: Yamanashi, Yoshihide, Takada, Tappei, Yamamoto, Hideaki, Suzuki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551898/
https://www.ncbi.nlm.nih.gov/pubmed/32872588
http://dx.doi.org/10.3390/nu12092641