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Two Novel Peptide Toxins from the Spider Cyriopagopus longipes Inhibit Tetrodotoxin-Sensitive Sodium Channels

Sodium channels play a critical role in the generation and propagation of action potentials in excitable tissues, such as nerves, cardiac muscle, and skeletal muscle, and are the primary targets of toxins found in animal venoms. Here, two novel peptide toxins (Cl6a and Cl6b) were isolated from the v...

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Detalles Bibliográficos
Autores principales: Zhang, Qingfeng, Si, Yuxin, Yang, Li, Wang, Li, Peng, Shuijiao, Chen, Yiming, Chen, Minzhi, Zhou, Xi, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551932/
https://www.ncbi.nlm.nih.gov/pubmed/32824960
http://dx.doi.org/10.3390/toxins12090529