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Going beyond Integration: The Emerging Role of HIV-1 Integrase in Virion Morphogenesis

The HIV-1 integrase enzyme (IN) plays a critical role in the viral life cycle by integrating the reverse-transcribed viral DNA into the host chromosome. This function of IN has been well studied, and the knowledge gained has informed the design of small molecule inhibitors that now form key componen...

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Detalles Bibliográficos
Autores principales: Elliott, Jennifer L., Kutluay, Sebla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551943/
https://www.ncbi.nlm.nih.gov/pubmed/32916894
http://dx.doi.org/10.3390/v12091005