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Going beyond Integration: The Emerging Role of HIV-1 Integrase in Virion Morphogenesis
The HIV-1 integrase enzyme (IN) plays a critical role in the viral life cycle by integrating the reverse-transcribed viral DNA into the host chromosome. This function of IN has been well studied, and the knowledge gained has informed the design of small molecule inhibitors that now form key componen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551943/ https://www.ncbi.nlm.nih.gov/pubmed/32916894 http://dx.doi.org/10.3390/v12091005 |