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A Surrogate Animal Model for Screening of Ebola and Marburg Glycoprotein-Targeting Drugs Using Pseudotyped Vesicular Stomatitis Viruses

Filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV), cause severe hemorrhagic fever in humans and nonhuman primates with high mortality rates. There is no approved therapy against these deadly viruses. Antiviral drug development has been hampered by the requirement of a biosafety leve...

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Detalles Bibliográficos
Autores principales: Saito, Takeshi, Maruyama, Junki, Nagata, Noriyo, Isono, Mao, Okuya, Kosuke, Takadate, Yoshihiro, Kida, Yurie, Miyamoto, Hiroko, Mori-Kajihara, Akina, Hattori, Takanari, Furuyama, Wakako, Ogawa, Shinya, Iida, Shigeru, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552044/
https://www.ncbi.nlm.nih.gov/pubmed/32842671
http://dx.doi.org/10.3390/v12090923