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Evaluation of the 50% Infectious Dose of Human Norovirus Cin-2 in Gnotobiotic Pigs: A Comparison of Classical and Contemporary Methods for Endpoint Estimation

Human noroviruses (HuNoVs) are the leading causative agents of epidemic and sporadic acute gastroenteritis that affect people of all ages worldwide. However, very few dose–response studies have been carried out to determine the median infectious dose of HuNoVs. In this study, we evaluated the median...

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Detalles Bibliográficos
Autores principales: Ramesh, Ashwin K., Parreño, Viviana, Schmidt, Philip J., Lei, Shaohua, Zhong, Weiming, Jiang, Xi, Emelko, Monica B., Yuan, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552045/
https://www.ncbi.nlm.nih.gov/pubmed/32872283
http://dx.doi.org/10.3390/v12090955