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Bile Facilitates Human Norovirus Interactions with Diverse Histoblood Group Antigens, Compensating for Capsid Microvariation Observed in 2016–2017 GII.2 Strains

Human norovirus (HuNoV) is the leading cause of global infectious acute gastroenteritis, causing ~20% of reported diarrheal episodes. Typically, GII.4 strains cause 50–70% of yearly outbreaks, and pandemic waves of disease approximately every 2–7 years due to rapid evolution. Importantly, GII.4 domi...

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Detalles Bibliográficos
Autores principales: Mallory, Michael L., Lindesmith, Lisa C., Brewer-Jensen, Paul D., Graham, Rachel L., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552067/
https://www.ncbi.nlm.nih.gov/pubmed/32899556
http://dx.doi.org/10.3390/v12090989