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Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2

Hepatitis B surface antigen (HBsAg) promotes persistent hepatitis B virus (HBV) infection. It primarily corresponds to small (S) envelope protein secreted as subviral particles. We previously found that genotype D clones expressed less S protein than genotype A clones but showed higher extracellular...

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Detalles Bibliográficos
Autores principales: Wang, Qianru, Fu, Shuwen, Zhang, Jing, Yuan, Quan, Li, Jisu, Xia, Ningshao, Wen, Yu-Mei, Wang, Yongxiang, Tong, Shuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552069/
https://www.ncbi.nlm.nih.gov/pubmed/32882910
http://dx.doi.org/10.3390/v12090967