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Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis

Spermatogonial stem cells (SSCs) both self-renew and give rise to progenitors that initiate spermatogenic differentiation in the mammalian testis. Questions remain regarding the extent to which the SSC and progenitor states are functionally distinct. Here we provide the first multiparametric integra...

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Detalles Bibliográficos
Autores principales: Cheng, Keren, Chen, I-Chung, Cheng, Ching-Hsun Eric, Mutoji, Kazadi, Hale, Benjamin J., Hermann, Brian P., Geyer, Christopher B., Oatley, Jon M., McCarrey, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552105/
https://www.ncbi.nlm.nih.gov/pubmed/33083754
http://dx.doi.org/10.1016/j.isci.2020.101596