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Toll-like receptor 4 (TLR4) expression is correlated with T2* iron deposition in response to doxorubicin treatment: cardiotoxicity risk assessment

Although doxorubicin (Dox) is an effective antitumor antibiotic in the anthracycline class, it often induces the undesirable side effect of cardiomyopathy leading to congestive heart failure, which limits its clinical use. The primary goal of this study is to evaluate a reliable translational method...

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Detalles Bibliográficos
Autores principales: Trofenciuc, Nelu-Mihai, Bordejevic, Aurora Diana, Tomescu, Mirela Cleopatra, Petrescu, Lucian, Crisan, Simina, Geavlete, Oliviana, Mischie, Alexandru, Onel, Alexandru Fica Mircea, Sasu, Alciona, Pop-Moldovan, Adina Ligia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552385/
https://www.ncbi.nlm.nih.gov/pubmed/33046755
http://dx.doi.org/10.1038/s41598-020-73946-9